Science Day Theme

From Discovery to Impact

As part of the National Institutes of Health (NIH), the All of Us Research Program (All of Us) is changing how health research is done – and ensuring that everyone benefits from it.

Our mission is to accelerate health research and make personalized prevention, treatment, and care possible for everyone. To achieve this, we’ve partnered with nearly 900,000 people across the United States who are sharing their health information to make it happen.

Because of their contributions, researchers are making discoveries faster than ever before. These discoveries are already helping improve health care today. Together, we are shaping a healthier future for generations to come.

All of Us is proof that when research includes everyone, discoveries lead to real-world impact.

Learn more about the All of Us Research Program

Accelerating Research Translation

The Path From Discovery to Impact

Every health discovery starts with a question. Participation fuels the answers. And answers lead to impact.

Researchers from across the country and around the world are using the All of Us dataset to explore thousands of health questions. It is one of the most comprehensive health resources ever assembled. Researchers can test ideas in hours that once took years and millions of dollars to study.

But discovery is only the beginning. With All of Us data, researchers are identifying disease risks earlier and learning more about how conditions affect different communities. They are uncovering safer medication combinations and accelerating the development of new treatments. What starts as data becomes insight. Insight becomes action. Action leads to better care.

This progress is only possible because of the trust and partnership of participants from across the United States and its territories. By sharing their information, participants are helping move science beyond the lab and into real-world impact. This means improving health today and shaping a healthier future for all of us.

search results underway Explore publications and research findings

Stories of Progress and Possibility

Accelerating Research

All of Us opened for national enrollment in 2018. Just two years later, researchers began using the program’s first dataset. Since then, the program has continued to grow in size and possibility.

Today, researchers can study health from many angles at once. They have access to participant surveys, genetic information, electronic health records, physical measurements, and wearable device data. Together, these create a research resource unmatched in its breadth and depth. With this resource, scientists can explore how biology, lifestyle, environment, and community collectively shape health.

This dataset continues to expand, with new data types added regularly. Research tools are becoming more powerful and easier to use. Recent updates to the Researcher Workbench make it simpler for scientists to explore information, test ideas, and collaborate across institutions. These enhancements help move promising findings forward more quickly.

To further accelerate discovery, All of Us will establish a pathway for researchers to study biospecimens shared by participants. Access to these biosamples opens the door to deeper insights into disease risk, treatment response, and prevention.

Thanks to the imagination of researchers and generosity of participants nationwide, discoveries that once took years are now happening in a fraction of the time. This is how science moves from discovery to impact.

Empowering Participants

Participants are at the heart of All of Us. Their partnership makes discovery possible and ensures that progress in science translates into better health for everyone. By sharing their health information and biosamples, participants are helping researchers uncover new insights into disease risk, treatment response, and prevention. At the same time, many participants receive information that can help them make informed decisions
about their own health.

For example, participants who volunteered to share blood or saliva contributed to one of the largest returns of genetic results in history. More than 5,400 participants have been notified of potential health risks. Over 140,000 have learned that their genes may influence how their bodies process certain medicines. These insights can support conversations with health care providers and guide personal care decisions.

Participants also have opportunities to engage in additional research. Partnered research studies offer even more ways to contribute and learn. Eyes on Health provides participants with information about how the eye connects to overall health. Through Nutrition for Precision Health, participants are helping scientists understand how genes, lifestyle, and environment influence how different people respond to different foods.

Through opportunities like these, participants are doing more than contributing data. They are helping move science forward while gaining knowledge that supports their own health and well-being.

Learn how to join All of Us

Improving Care

Discoveries powered by All of Us data are already helping health care providers make more informed, personalized decisions
about prevention and treatment.

For example, researchers studying DNA data from more than 245,000 All of Us participants identified a rare genetic difference that affects how certain chemotherapy medicines work. As a result, clinical guidance was updated so doctors can make safer and more precise treatment decisions for patients who carry this variation.

In another study, researchers used All of Us data to better understand how inherited differences influence the risk of cardiovascular disease. This work led to the development of a new clinical test that doctors can use to assess a person’s risk for conditions such as heart disease, diabetes, and high blood pressure. Clinical tools like this enable earlier action and more tailored care.

These examples show how discovery moves beyond research findings and into exam rooms, communities, and everyday health decisions.

Shaping the Future Together

All of Us is proof that when everyone is included, science moves from discovery to real-world impact.

All of Us participants and researchers are working together to build one of the most powerful research resources in history, and to ensure that its benefits are shared broadly.

At Science Day 2026, we celebrate the discoveries already improving care today and look ahead to what comes next. Every question explored, data point shared, and insight uncovered brings us closer to a future where health care is more precise and effective for all communities.

Thank you for being part of this journey, and for helping turn discovery into lasting impact.